The San Francisco 49ers (5-6) try to salvage their season against the Buffalo Bills (9-2) on Sunday Night Football. Kickoff ...

San Francisco's starting quarterback missed last week's loss to the Packers. Here's the latest on whether he'll play in primetime on Sunday.

As the 49ers prepare for their Week 13 matchup against the Bills, Brock Purdy will be the signal caller after being listed as ...

QB Brock Purdy injured his shoulder in Week 11 against the Seattle Seahawks and wound up missing the team’s blowout Week 12 ...

Fantasy managers may need to proceed with caution before placing San Francisco's offensive players in their lineup this week.

The San Francisco 49ers have slim playoff hopes of their own, but they can also play spoiler against the Buffalo Bills in ...

San Francisco 49ers vs Buffalo Bills showdown with essential stats, lineup predictions and injury updates you won’t want to ...

It's Week 13, and the San Francisco 49ers are at 5-6 in the season. The team travels to Buffalo to take on the leaders of the ...

The San Francisco 49ers will travel to take on the Buffalo Bills in Week 13. Here’s the final injury report and start-sit advice for every skill player who has the potential to make a fantasy football ...

the San Francisco 49ers aren't among the favorites to win the Super Bowl this season. The 49ers picked up a 38-10 loss to the Green Bay Packers in their last game. Brandon Allen had 199 yards on ...