Colin Cowherd believes that the Buffalo Bills are the best team in the NFL when playing at full strength. Somebody forgot to ...

San Francisco has been up and down all season, but the Super Bowl hangover appears to be happening after the 49ers got ...

Former Buffalo Bills quarterback Ryan Fitzpatrick recently sang the praises of current field general Josh Allen.

The Buffalo Bills will play the San Francisco 49ers at home at Highmark Stadium on "Sunday Night Football" in Week 13. The ...

Former Buffalo Bills defensive end Leonard Floyd spoke about facing his old team on Sunday night with the San Francisco 49ers ...

Now that the holiday season is in full swing, several Bills players are taking the time to be active in the community. A ...

Following their bye week, the Bills (9-2) will take on the San Francisco 49ers (5-6) at Highmark Stadium in Week 13. But ...

The AFC East-leading Buffalo Bills return from their bye week to host the inconsistent San Francisco 49ers on Sunday night.

Before you make any Week 13 NFL picks, be sure to see the exact NFL score predictions from SportsLine expert Eric Cohen.

Buffalo Bills coach Sean McDermott looked and sounded refreshed as he and his team returned from its bye week.

The highly anticipated Buffalo Bills clash against the San Francisco 49ers, scheduled for Sunday at Highmark Stadium, faces ...

The Buffalo Bills are heading out of the their bye and are set to face the San Francisco 49ers in Week 13 on “Sunday Night ...