Wednesday practice report is starting to have two constants for the San Francisco 49ers. Those two constants are star players ...

The San Francisco 49ers on Wednesday continued adjusting to life without running backs Christian McCaffrey and Jordan Mason.

The physical brand of football the 49ers play is something Thomas Brown wants the Bears to emulate but the question is ...

McCaffrey should be fine long term, though it's hard to say whether he'd be able to play again this season if the 49ers made ...

The San Francisco 49ers and fantasy football players who were relying on the NFC West team's running backs are probably all ...

A spate of injuries has derailed the 49ers' Super Bowl hopes his season, but the bigger question is if their title window has ...

The San Francisco 49ers on Tuesday announced how they’d replace running back Christian McCaffrey. In a slew of roster moves ...

The San Francisco 49ers claimed running back Israel Abanikanda off waivers from the New York Jets on Tuesday, one day after ...

The 49ers brass — Kyle Shanahan, John Lynch, and CEO Jed York chief among them — have not wavered on their commitment to ...

The Bills are a Super Bowl contender and the 49ers somehow probably aren’t even a playoff team. That’s how Sunday night’s ...

It's Buffalo Bills vs San Francisco 49ers in Week 13 of the NFL season. Can Josh Allen and company outduel Christian ...

Christian McCaffrey is dealing with an injury again. The 49ers running back went down with a knee injury in the second ...