The 49ers just lost 35-10 to the Buffalo Bills. Now the 49ers are 5-7 and all alone in last place in the NFC West. Here are their grades for this per ...

The swagger is officially gone from this season's 49ers after another miserable outing in a 35-10 loss in Buffalo.

Buffalo Bills star Quarterback Josh Allen writes his name in NFL history books after do-it-all performance against the San ...

The Buffalo Bills easily got past the San Francisco 49ers 35-10 on a snowy Sunday Night Football matchup. Here are winners ...

Temperatures reached the 20s Sunday night as snow fell throughout Buffalo’s Week 13 home game against San Francisco. For the ...

The Bills return from their bye and will look to keep pace with the Kansas City Chiefs at the top of the AFC. Josh Allen has ...

Follow along for updates throughout the game as the Buffalo Bills take on the San Francisco 49ers at snowy Highmark Stadium.

The San Francisco 49ers now have their backs against the wall. Up next is the Green Bay Packers at Lambeau Field, a rematch of the recent divisional round playoff game in which San Francisco ...

The San Francisco 49ers and Green Bay Packers play on Sunday, Nov. 24 at Lambeau Field in a game on the NFL Week 12 schedule. Which team will win the NFL Week 12 game? The Packers are a 2.5-point ...

SAN FRANCISCO -- In a city with a bustling cocktail and culinary scene, San Francisco's Hotaling & Co. stands out with its innovation-first approach and one of the only distilleries operating at ...

The Seattle Seahawks will travel to the Bay Area and take on the San Francisco 49ers in an NFC West divisional matchup at 4:05 pm ET Sunday afternoon. The Seattle Seahawks are currently 4-5 and ...