Wide receiver Chris Conley, linebacker Curtis Robinson and more San Francisco 49ers players shared what they're most grateful ...

A young San Francisco 49ers fan was viciously trolled by 'Transformers' character Megatron during a visit to Universal ...

The nightcap of Sunday's action will be in northern New York with the Buffalo Bills (9-2) hosting the San Francisco 49ers (5-6). San Francisco has been up and down all season, but the Super Bowl ...

The Buffalo Bills dominated the San Francisco 49ers on Sunday night, winning 35-10 in Highmark Stadium in Orchard Park, N.Y. Josh Allen had a unique stat line for the night. He was credited with a ...

Fantasy football analyst Matt Harmon delivers his thoughts on the major happenings of Week 13's Sunday action.

The San Francisco 49ers have been to two Super Bowls in the last five seasons, and two NFC Championship games in two of the other three, but this year they're in danger of missing the playoffs ...

Orchard Park, N.Y. — The Buffalo Bills take on the San Francisco 49ers at 8:20 p.m., Sunday at Highmark Stadium. The game will air on NBC. Snow removal crews have been working around the clock ...

In NFL week 13, the San Francisco 49ers vs. Buffalo Bills game will be played at Highmark Stadium. The 49ers currently hold a less-than-stellar record of 5-6, and they are currently on a two-game ...

The Buffalo Bills will look to clinch the AFC East on Sunday with a win against the San Francisco 49ers in what's expected to be a snowy night in Orchard Park. On the injury front, the Bills ...

Josh Allen and the Buffalo Bills host Christian McCaffrey and the reeling San Francisco 49ers in Week 13 on Sunday Night Football. Live coverage begins at 7:00 PM ET with Football Night in America on ...