The San Francisco 49ers look ready to make Brock Purdy their QB of the future, but they may need to act fast to get it done ...

San Francisco 49ers star running back Christian McCaffrey will not need surgery on his injured right knee but he will miss the rest of the regular season.

Joe Montana is a Hall of Fame quarterback for the 49ers and Chiefs. Here is a look at Joe Montana's incredible $171K car ...

The San Francisco 49ers hosted a fan-focused event with the 49ers Pride Fan Group and PLUS (LGBTQ+) ERG to discuss being out ...

The Buffalo Bills host the San Francisco 49ers on Sunday Night Football in a week 13 clash.The Bills (9-2) are coming off six ...

On a snowy night in Orchard Park, N.Y., the Buffalo Bills clinched the AFC East title with a dominant win over the San ...

The Bills are a Super Bowl contender and the 49ers somehow probably aren’t even a playoff team. That’s how Sunday night’s ...

That was one of the many highlights for the home team, while the 49ers (5-7) dropped another game behind the ... left guard ...

Micah Roberts, on a 25-6 run on San Francisco 49ers picks, has revealed his Sunday Night Football expert picks for San ...

San Francisco 49ers RB Isaac Guerendo sped past the Buffalo Bills defense for a touchdown on "SNF" San Francisco 49ers RB ...

The National Weather Service has extended its "lake effect snow warning" in Buffalo through Monday at 7 p.m. ET, with ...

The 49ers won't have their best pass rusher when they face the Bills on Sunday. Nick Bosa will miss his second game in a row with an oblique injury ...