The Buffalo Bills might have a chance to clinch the AFC East on Sunday night when they battle the injury-decimated San ...

The San Francisco 49ers are reeling and now head to Buffalo for a prime time game. Will they have their starting QB back in ...

Brock Purdy missed the 49ers' last game against the Packers, but the Bills are preparing as if he's playing on Sunday night.

The 49ers are welcoming Brock Purdy back to practice today after shoulder soreness kept him out of Sunday’s loss at Green Bay.

SANTA CLARA — While Brock Purdy resumed practicing through a shoulder issue and Dre Greenlaw made a much-anticipated debut ...

All six of the NFL teams playing on Thanksgiving will be without critical players. The Chicago Bears will be without center ...

Bad news for the 49ers. Brock Purdy still isn't ready to resume throwing. Technically, he threw one pass on Wednesday -- a screen pass that floated ...

The banged-up San Francisco 49ers received some positive news on Wednesday. Per ESPN's Nick Wagoner, 49ers head coach Kyle ...

LB Fred Warner, WR Deebo Samuel Sr., RB Christian McCaffrey and DL Nick Bosa identified key areas for improvement as the team ...

The 49ers have revealed their latest injury report from Wednesday’s practice before their Sunday Night Football tilt against ...

In Week 12, the Green Bay Packers made a statement on their home field at Lambeau Field by crushing the defending NFC ...

There's no denying that it's trending towards a lost season for the San Francisco 49ers. What was once a season with so much ...