The San Francisco 49ers looked nowhere near the team that made it to the Super Bowl last season. Kyle Shanahan's men are 5-7 ...

See what Kyle Shanahan, Brock Purdy, Sean McDermott and Josh Allen had to say following the Week 13 primetime contest.

“Frostbite is a freezing injury to the body’s tissues caused by prolonged exposure to cold,” Johns Hopkins Medicine says. “It ...

After sparking the 49ers with a handful of impressive runs, Christian McCaffrey looked like himself early in the game against ...

The swagger is officially gone from this season's 49ers after another miserable outing in a 35-10 loss in Buffalo.

If you didn't know the San Francisco 49ers were Super Bowl contenders last season, you might not believe it now. The 5–6 team ...

Buffalo Bills fans are a different breed. They smash flaming tables, drink out of bowling balls, slide down makeshift snow ...

The 49ers had three fumbles in Sunday night's contest, all three of which were recovered by the Bills. San Francisco's ...

The San Francisco 49ers needed a win Sunday at Levi's Stadium against the Seattle Seahawks. Instead, they turned in a dud that saw a disjointed offense plagued by mistakes, wasting a strong ...

The Seattle Seahawks will travel to the Bay Area and take on the San Francisco 49ers in an NFC West divisional matchup at 4:05 pm ET Sunday afternoon. The Seattle Seahawks are currently 4-5 and ...

Call it a bad case of the Sundays. San Francisco 49ers wide receiver Deebo Samuel was seen with his hands around the neck of a teammate — long-snapper Taybor Pepper — late in the fourth ...