Under head coach Kyle Shanahan, the San Francisco 49ers have spent years falling just inches short of the franchise’s sixth ...

How have Super Bowl odds changed over the last week? Let's take a look at the most recent sports betting odds for Super Bowl ...

San Francisco 49ers three-time Super Bowl champion has suddenly passed away at 80, the team announced on Thursday.

While the 49ers look like an easy opponent, San Francisco's health could be a major factor in the game, warns one NFL expert.

John and Jim Harbaugh have met as head coaches on the biggest stage in football, colliding back in Super Bowl 47.

The San Francisco 49ers have lost back to back games and are losers in three of their last five, falling to 5-6 on the season ...

The banged-up 49ers suffered a blowout loss to the Packers on Sunday, and their playoff outlook is becoming more bleak.

Calling Sunday's loss to the Seattle Seahawks disappointing is an understatement, especially for San Francisco 49ers legend ...

Sunday's loss to the Seahawks was another offensive slog for a team that isn't looking very Super Bowl-hopeful so far this ...

For as up and down as the San Francisco 49ers have been as a franchise ever since Steve Young retired, we are firmly in the ...

NFL Week 13 odds, picks, predictions, TV and streaming information for Sunday Night Football game between the San Francisco ...