For as disjointed and dry as the 49ers are offensively, it's their run defense that has crushed their chances and led to road ...

Fantasy football analyst Matt Harmon delivers his thoughts on the major happenings of Week 13's Sunday action.

The 49ers’ third straight defeat came in 35-10 fashion to the AFC East-clinching Buffalo Bills amid a snowstorm at Highmark ...

Finally, it's over. The San Francisco 49ers suffered an abysmal 35-10 loss to the Buffalo Bills. It wasn't a close game at all for the 49ers. Buffalo was in con ...

Running away with the AFC East: For the fifth consecutive season, the Bills are AFC East champions. This season was ...

Before the 2024 NFL season, Sunday night's Week 13 matchup between the Buffalo Bills and San Francisco 49ers might've been ...

The table is set for the Bills to clinch a fifth consecutive AFC East title in prime time on WGRZ-TV. Expect them to deliver.

San Francisco 49ers linebacker Fred Warner exited with cramps, but then later returned in the first half vs. the Buffalo ...

San Francisco 49ers quarterback Brock Purdy is active for the team's Week 13 matchup versus the Buffalo Bills.

A pair of Super Bowl hopefuls from each conference meet up on Sunday, Dec. 1 to close out the NFL schedule for the day with ...

While the 49ers welcome Brock Purdy back to the starting lineup at snow-covered Highmark Stadium, his immediate backup will ...

Philadelphia Eagles' defensive lineman Jalen Carter chases down Baltimore Ravens' quarterback Lamar Jackson for a 12-yard ...