San Francisco running back Christian McCaffrey suffered a knee injury that coach Kyle Shanahan described as "potentially" ...

Before the 2024 NFL season, Sunday night's Week 13 matchup between the Buffalo Bills and San Francisco 49ers might've been ...

Running away with the AFC East: For the fifth consecutive season, the Bills are AFC East champions. This season was ...

The 49ers’ third straight defeat came in 35-10 fashion to the AFC East-clinching Buffalo Bills amid a snowstorm at Highmark ...

The tragedy of this 49ers’ season epitomized. For the first time since returning to the lineup in Week 10, McCaffrey looked ...

A pair of Super Bowl hopefuls from each conference meet up on Sunday, Dec. 1 to close out the NFL schedule for the day with ...

Defeating the Buffalo Bills on the road will be extremely difficult for the San Francisco 49ers. Going to the East Coast when ...

Ahead of Week 12, Bleacher Report's Scouting Department urged the Indianapolis Colts to sign former All-Pro San Francisco ...

The Bills will not have one of their key offensive players for Sunday’s game against the 49ers, though they could get one of ...

Purdy is officially listed as questionable for the game, though coach Kyle Shanahan said the plan is for him to start on ...

There are no teams on bye around the NFL in Week 13, which means we'll be treated to a packed slate of Sunday games even ...

It’s not like he was throwing at game speed, but the sight of Brock Purdy throwing the ball during warmups Friday was ...