Background Patient perception of asthma treatment is rarely captured, and no specific tools exist to measure it. We developed an inhouse severe asthma patient feedback questionnaire (SAPFQ) using ...

Rationale Endoscopic lung volume reduction improves lung function, quality of life and exercise capacity in severe emphysema patients. However, its effect on the diaphragm function is not well ...

Introduction and Objectives Oral corticosteroids (OCS) are sometimes used to manage exacerbations in patients with chronic obstructive pulmonary disease (COPD). Evidence suggests chronic OCS use is ...

BACKGROUND In a retrospective study the value of bronchoalveolar lavage (BAL) in the diagnosis of pneumonia was investigated in 95 immunocompromised patients suffering from haematological disorders ...

Asthma exacerbations are common. They account for a significant morbidity and contribute a disproportionate amount to the cost of asthma management. The optimal strategies for the prevention of asthma ...

Rationale Progressive lung function (LF) decline in patients with asthma contributes to worse outcomes. Asthma exacerbations are thought to contribute to this decline; however, evidence is limited ...

Introduction Tezepelumab, a human monoclonal antibody targeting TSLP, inhibits T2 inflammation leading to a fall in both the blood eosinophil count (Eos) and fractional exhaled nitric oxide (FeNO) ...

2 Department of Respiratory Medicine, National Heart and Lung Division, Imperial College, London W2 1PG, UK Correspondence to: Dr med J Schwarze Department of Respiratory Medicine, National Heart and ...

Introduction Bronchiectasis is a chronic, progressive lung condition which has significant effects on quality of life (QOL). Quick patient reported outcome measures (PROMs) measuring QOL are limited ...

1 Department of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong 2 Department of Psychiatry, Shatin Hospital, The Chinese University of Hong Kong, Shatin, ...

Background Smoking and severe asthma exacerbations in pregnancy are risk factors for low birth weight babies. No studies have assessed the clinical implications of smoking on asthma exacerbations in ...

Introduction Air pollution is associated with increased asthma-related admission rates (Lancet, 2014;383(9928):1581–92). The impact of pollution on outcomes of monoclonal antibody (MAb) therapy in ...