Double-edged STING: A new pathway involved in aging
A protein called STING, previously shown to control a pathway that contributes to antiviral signaling, also plays an ...
Protein signaling pathway provides insights into cell migration and cancer metastasis
However, our data suggest that 2'3'-cGAMP could also activate Rab18/FosB signaling pathway—but not the well-studied ...
EurekAlert!8mon
cGAS-STING pathway response model for micronucleus (IMAGE)
An artist's impression of cGAS-STING pathway response model for micronucleus. Before, cGAS's accumulation in micronuclei was considered to be an indicator of cGAS activation. Now, it was found ...
EurekAlert!7mon
The cGAS-STING pathway facilitates crosstalk between cancer cells and the tumor microenvironment (TME). (IMAGE)
The cGAS-STING pathway facilitates crosstalk between cancer cells and the tumor microenvironment (TME). The activation of cGAS-STING promotes the release and presentation of cancer antigens ...
Nanowerk3y
cGAS–STING cytosolic DNA sensing pathway
The cGAS–STING pathway is a component of the innate immune system that ... Upon recognition of a PAMP, PRRs generate signal cascades leading to transcription of genes associated with the immune ...