These signalling systems operate beyond cell ... Figure 3: Cancer therapeutics that target components of the canonical Wnt pathway. Recent studies suggest that so-called cancer stem cells, which ...

Type 2 diabetes (T2D) and obesity (OB) are associated with chronic low-grade inflammation and increased fracture risk. In vitro studies showed that inflammation induces bone erosion and inhibits bone ...

Intriguingly, the expression of the MLH1 gene, crucial for DNA repair, was influenced by the activity of the Wnt signaling pathway. In MSI patients, the canonical Wnt signaling pathway was notably ...