Weill Cornell Medicine researchers have determined the full-length structure of a blood pressure-regulating hormone receptor ...

Weill Cornell Medicine researchers have determined the full-length structure of a blood pressure-regulating hormone receptor for the first time, uncovering how it functions, which may enable better ...

BAFF-R = BAFF receptor; BCMA = B-cell-maturation antigen; MS = multiple sclerosis; TACI = transmembrane activator and calcium modulator cytophilin ligand interactor. B cells are clonally expanded ...

BMS, says Kaiser, is tripling down on BCMA across different modalities. Multiple avenues for therapy Among these novel modalities, chimeric antigen receptor (CAR) T cells have the longest history ...

At present, dozens of BCMA-targeting therapies — such as chimeric antigen receptor T (CAR-T) cells, bi-specific antibodies and antibody-drug conjugate — are being developed and clinically tested.

Transmembrane signaling systems include membrane-bound cell surface receptors and molecules called ligands that bind to these receptors. In its most general use, "ligand" is a term for something ...